A FLUOROMETRIC METHOD FOR THE DETERMINATION OF THE 6-PYRIDONE OF N1-METHYLNICOTINAMIDE IN URINE
نویسندگان
چکیده
منابع مشابه
A fluorometric method for the determination of the 6-pyridone of N1-methylnicotinamide in urine.
Since Knox and Grossman demonstrated the excretion by man of the 6-pyridone of N’-methylnicotinamide (hereafter referred to as the pyridone) in appreciable amounts after the ingestion of nicotinamide (2), it became necessary to devise a method for its quantitative estimation in urine. Knox and Grossman isolated the compound from human urine and described its properties, including its ultraviole...
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A simple method for the determination of N1-methylnicotinamide in urine.
N1-methylnicotinamide (MNA) is found in urine as an assymilation product when administered as nicotinic acid or nicotinamide. MNA was extracted from urine as a pure product and its physicochemical properties reported (4-6). Its maximum adsorption is reported by Hochberg, Melnick, and Oser (4) to lie at 265mƒÊ, E1cm1% 265mƒÊ=258 at pH 9.7. It is stable in urine in the dark for one week, even in ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1949
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)56823-x